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p3analyze

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p3analyze

Re: walldiver post# 51502

Friday, 08/24/2007 10:55:39 PM

Friday, August 24, 2007 10:55:39 PM

Post# of 253498
"and an HR of 0.67 in interim overall survival aren't marginal results"

One of the slide in the linked ppt http://www.unich.it/mso.cinbo/eng/courses/2006/2006111617slides/1711am/13_Ciardiello.ppt
showed a hazard ratio of 0.84 with p=0.12, was this after ealy stopping followed by taxol patients cross-over. Will this BLA update the long term OS data? Given what's shown here, at 50% information, the liklihood of final OS significant would be very low. Perhaps FDA saw this coming at time of first review?
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