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Thursday, 08/16/2007 12:06:59 PM

Thursday, August 16, 2007 12:06:59 PM

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PR NEWSWIRE Benitec MOU With CalbaTech, Inc.

Stem cell storage service connected with potential Benitec HIV therapy

MELBOURNE, Australia, Aug 16., 2007 /PRNewswire-FirstCall via COMTEX/ -- Benitec

Limited (ASX: BLT) has signed a Memorandum of Understanding with California-based CalbaTech, Inc. (CLBE) to provide stem cell storage services for US HIV patients who may use the healthy adult (or “blood” or “hematopoietic”) stem cells in future therapy.

Benitec has collaborated with City of Hope, a biomedical research and treatment center, in the development of a possible HIV therapeutic. This investigational HIV therapeutic creates the possibility that an adult (or “blood” or “hematopoietic”) stem cell based therapeutic may be able to take the place of anti-retroviral medication. Early banking of adult (or “blood” or “hematopoietic”) stem cells by HIV sufferers may be very prudent if a stem cell therapy is approved by the FDA after the conclusion of clinical trials.

This potential therapy surrounds a newly discovered possible way in which to fight HIV, the virus that causes AIDS, with genetically modified adult (or “blood” or “hematopoietic”) stem cells. The potential therapeutic may emerge as the first to use specially engineered, HIV-fighting genes that are inserted into patients’ own harvested adult (or “blood” or “hematopoietic”) stem cells. After re-infusion into the patient, the new treatment may allow patients’ bodies to produce HIV-resistant white blood cells indefinitely.

Benitec’s MOU with CalbaTech would provide, in the short term, that Benitec would receive fees for stem cell storage performed by CalbaTech’s subsidiary, TherapyStem, Inc. In the longer term, both Benitec and CalbaTech are encouraged that this potential new therapeutic will develop an effective HIV therapeutic that relies on healthy adult (or “blood” or “hematopoietic”) stem cells. CalbaTech believes that, in the future, as this potential therapeutic develops, TherapyStem will be able to treat the cells that have been banked by HIV patients and send those treated cells to a patient’s treating physician for re-injection. CalbaTech would pay to Benitec a fee for using the protocols developed for the treatment of the stem cells.

CalbaTech’s new subsidiary, TherapyStem, Inc., has created a patent-pending., process to harvest stem cells from HIV infected individuals to be cryopreserved for future transplantation into a client for medical purposes. All other stem cell collection services exclude the collection, processing and storage of blood from individuals with HIV. As the business of TherapyStem develops, the company also believes that it will be able to collect, process and store stem cells from umbilical cords that have come from a mother that has HIV. Those cords are currently excluded from collection by cord blood companies.

CONTACT:
BENITEC LTD
Sue MacLemanRudi Michelson
Chief Executive OfficerMonsoon Communications
+61 437 211 200+61 411 402 737

About Benitec
Benitec is an Australian biotechnology company focused on licensing its extensive intellectual property portfolio and developing therapeutics to treat serious diseases using its proprietary ddRNAi technology. Its current therapeutic program is focused on Human Immunodeficiency Virus (HIV). Benitec’s RNA-based HIV therapeutic, co-developed with City of Hope in Duarte, California, is currently in Phase I trial at City of Hope. For additional information, please visit http://www.benitec.com.
Paul Knopick
E & E Communications
949/707-5365



About CalbaTech
CalbaTech, Inc. (CLBE) is an emerging life sciences company
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