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Re: spartex post# 50246

Wednesday, 07/25/2007 8:09:05 PM

Wednesday, July 25, 2007 8:09:05 PM

Post# of 252468

Yes. The fact that there were no hyperplasias, EIN, or carcinomas far outweighs novel the novel cytopathology.

Proellex is a drug that affects the endometrium, of course it's going to have a structural effect. The fact that they're seeing poor secretory activity and apoptotic cells argues that this is a phenomenon associated with aging of a tissue that is normally turned over rapidly. I'd suspect that intermittent shedding with a pulsed dose will eliminate this issue.

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