Entremed (ENMD)

[nottadoc2]

Re the GBM poster.

Cecee's brother appears to be the one blessed patient with a partial response. Reasonable to conclude Jerry from East Tennessee is included in the stable disease group. If I understand the poster, the pharmacokinectics were poor for those taking "EIAED"s-- Enzyme Inducing Anti Epilectic Drugs. How essential are these for patients ? Is the particular need for those with brain cancer?

As a general rule I think we have to accept that their conclusion as to "patients with recurrent GBM" --that 2ME2 as a monotherapy has "minimal activity"-- is probably true for recurrent cancers of all kinds and may be true for usage as a first treatment, which we will probably never see. As an adjuvant therapy, it still looks very promising, as far as I can see. Economically that may not be so bad. Notwithstanding lycopene, ketchup by itself is a terrible entree, but Heinz continues to sell a lot of it.