Thursday, May 17, 2007 2:04:40 PM
It's my understanding that the Ancestry based application can be used to (A) narrow down the pool of possible "responders" to a specific diagnostic haplotype, and (B) assign probabilities-of-response to unscreened individuals by bio-geographical association to existing "responder" groups. But to be used clinically, each individual would have to be screened genetically to determine if they had specific genetic sequences (cheaply, by haplotypes, if correlation is high) or by direct sequencing.
An Ancestry analysis can't tell me if I will individually (specifically) have a negative or positive reaction to a drug treatment, only that I am in a group already shown to correlate with a certain response and that I might need further testing.
Godd Luck!
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