>Since 01 gave a P=.002 with only about 90 events , 02A got p=.023 with about 70 events , and the integrated dataset yielded a P=.0006 with ~160 events… it seems like an interim look [in 9902b] at ~180 events would have much better than 50% odds of hitting a P of .015.<
The p-values you cite for 9901 and 9902a are based on cherry-picked Cox analyses. In 9902b, the primary endpoint will be based on a Cox analysis that is fully pre-specified.
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