Dendreon Corp fka DNDNQ

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With 500 patients, 9902b will be much more balanced than the integrated 9901+02a dataset. Although Cox should give more precision than log-rank, the p-value improvement might not be much more. So for the purpose of simulation, it might be better to just do log-rank since we have no data on the prognostic factors per each data point. What do you see as the power of the trial with HR=1.20 or HR=1.40? Same question for the interim result if N=180 or N=240?