Biotech Values

[ipollit77]

DNDN - >One can reach all kinds of strange conclusions by playing with median values the way you did.<

1.) all OS numbers published by DNDN are median survival values (50th percentile)... the whole provenge BLA is based on median survival

2.) from my point of view i didn't played with median numbers... but i've tried to adjust the official KM survival curve by take out the taxotere treated patients (on the assumption of the linear decreasing KM curve of this subgroup showed in the above slide). the resulting curve gives you not only the 50th median value but also 10th, 20th or whatever you want...

3.) the question for me was... what influence has taxotere treatment (or chemo) on the official survial values of D9901 or D9901+D9902A by taking into account that the median survival of tax+provenge (34.5 months, N=51) from both studies was nearly the full study timespan of 36 months. In the case of the integrated D9901+D9902A results the OS(MS) numbers go down from 23.2 to 19 months - that tells me the adjusted KM survival curve...

what is provenge worth without taxotere? Can you tell me?