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Re: philsdaddy post# 1460

Saturday, 04/28/2007 9:47:35 PM

Saturday, April 28, 2007 9:47:35 PM

Post# of 6451
NO such thing as a (sincere) stupid question

If Prehistin is, in essence, a synthetic fom of B12, then why can't people just take B12?

I'll take a stab at your very good question.
First of all, Prehistin is not synthetic B12--it's the real thing. B12 is not made in the human body, so Prehistin is the same stuff you get from food, a B12 shot, or a B12 pill.

So, what's wrong with taking a pill? Nothing if it does what you want it to do. If the goal is to increase the B12 level enough to treat deficiency, then everyone except those less than 1% of people with pernicious anemia (people who can not absorb B12) will be treated effectively by a pill and even that is unnecessary if they eat even a few servings of fresh foods and dairy products per year.

But let us digress to the hokier realm of belief, rather than accepted science. There is a ton of anecdotal belief and some research that B12 in megadoses works wonders on the immune system, the psyche, and a myriad of other organ systems. Many patients and their medical providers attest to the benefits from megadoses of B12. But the medicine is usually administered by injection because of the belief that oral doses can not produce the effect seen with megadose parenteral doses. In other words, the drug seems to act differently in huge doses directly into the bloodstream than just exposing the gut to a huge dose. In fact, our kidneys just piss away any B12 that our body does not "need". But, the critical and mysterious notion that keeps B12 so popular is that it seems to do wonderful things to the body when delivered systemically in megadoses.

So, my short answer to your question is that Prehistin provides patients a way to get megadoses of B12 without an injection. That's all.

As an interesting corollary, it follows from the above that Monday's (or whenever it happens) results won't necessarily be a binary event. Even if Prehistin fails for allergic rhinitis, I feel there will be plenty of interest in trying it for any number of other ailments, even for pernicious anemia. We'll all be paupers by then, but I am confident that Pre-histin in some form will be on the market in the near future.

Now, since most of believe Cobalis will announce positive results next week, let's have a little fun. See my next post.

Urche
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