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Re: ruengies3 post# 5543

Wednesday, 04/25/2007 6:25:07 AM

Wednesday, April 25, 2007 6:25:07 AM

Post# of 52240
Ruengies, Based on the large volume (over 800,000 shares), there's probably some type of mutual fund or other institutional buying starting. There was major interest in Cortex last year after the stellar ADHD results (sending the stock near $6), and those folks have likely been following the saga and now see the resolution coming soon. There are also numerous hedge funds out there who have been aware of Cortex's potential. Also, increasing activity should soon bring in the momentum crowd. Of course another possibility is that Dew and his buddies have decided to grab large chunks of Cortex stock. And with Dew onboard, can Cramer be far behind? :o)

The recent strongly worded press release was likely a factor, with Dr. Stoll using phrases like "there is CLEAR evidence", and "the FACT that the histo changes occur postmortem". In Dr. Stoll's mind there appears to be no ifs or buts about it. Coming from him that carries considerable weight, since he's always been a straight shooter and low key.

Another factor may be the realization that the dosing decision is likely going to come out of the blue, and fairly soon, and possibly independent of any 60 day clock. As Dr. Stoll indicated in his email, the requested face to face meeting with the FDA and it's theoretical 60 clock is for discussions on the Phase 2b ADHD IND, not for the dosing decision. This is a key piece of info, and means that the FDA could realistically issue their dosing decision at ANY time. There was a lot of data submitted, but all they really need to do is zero in on the target organ and electron microscope pictures, which could be accomplished quickly. Dr. Stoll called the data compelling. With unambiguous data, the FDA's decision could be cut and dried. As an investor therefore, one has to be in the stock or risk missing the boat completely.

Another factor I find heartening are Dr. Stoll's comments that the FDA has been reasonable, that their interactions have been constructive, etc. That's a key element, and having the FDA consultants on board from the beginning has undoubtedly helped in that regard.

Fwiw, I see the mid $3s over the next couple weeks.






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