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Re: drbio45 post# 44546

Sunday, 04/08/2007 12:11:16 PM

Sunday, April 08, 2007 12:11:16 PM

Post# of 252588
correction to orbec data

On intention-to-treat analysis, oral BDP was associated with 37% and 45% reductions in the risk of GVHD-treatment failure at study day 50 and at 30 days follow-up, respectively. The corresponding risk reductions among patients eligible for the prednisone taper at day 10 were 61% and 62%.

By day 200 after transplantation, 5 BDP-treated patients had died compared with 16 control patients, a risk reduction of 67% (p = 0.03). The reduction in mortality risk with BDP was even more pronounced among subjects who had received unrelated and HLA-mismatched stem cells -- 91% (p = 0.02). The survival benefit was still apparent 1 year after randomization.


The P value at 200 day survival is .013, not .03

As I said the data is not supericially similar, Provenge data doesn't come close

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