GTC Biotherapeutics (fka GTCB)

[biophud]

Question for Dew: Re GTC/Abgenix anti-IL-8. I assume that this program is dead (?) However, I think that the gist of my questions applies to other MAB companies as well.

http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/05-02-2000/0001206528&...

I thought an advantage making ABs in transgenic mice was to generate an antibody cell-line (without need of additional engineering) that could be grown in large-scale tissue culture for production.

I have wondered why ABGX wanted to use GTC’s goats. Engineering producing goats takes time and money? Are the goats such good protein producers that it is more economical than production via tissue culture? Will the goats replace large-scale tissue culture production methods?

biophud