In just a little googling on this I get the impression that this condition may be largely cytokine-related , with many similarities to sepsis. Steroids are obviously aimed at damping down this reaction but specific immune deficiencies may contribute as well , paradoxical as that may sound , and correction of these deficiencies with the appropriate CSF(s) , iv gamma-globulin , etc. , might help.
An example in HIV-related lymphoma :
"Persistent Panhypogammaglobulinemia After CHOP-Rituximab for HIV-Related Lymphoma "
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