Dendreon Corp fka DNDNQ

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biologically explain why a therapy is at a disadvantage to no therapy at all?

Sounds like your reasoning went something like this:

1. The DNDN pumpers claim that Provenge is at a disadvantage because TTP did not get stat sig due to some weird delay effect.
2. But it's being measured against placebo.
3. Ergo, they are claiming that it is disadvantaged against placebo.

A link in that chain of reasoning is missing.