Biotech Values

[biocqr]

Not that I'm aware of so I asked Chat GPT....

Q: Are there any drug companies working on developing the protien reelin?

A: Reelin, a protein encoded by the RELN gene, plays an important role in brain development and function.
It has been linked to various neurological conditions, including Alzheimer's disease and schizophrenia.
Some companies and research teams are investigating the potential of targeting the Reelin pathway for therapeutic purposes. For instance, studies have shown that Reelin might protect against Alzheimer's disease by modulating synaptic and neuronal functions, and a rare variant called Reelin-COLBOS has been associated with reduced Alzheimer’s symptoms in certain cases. Moreover, research into Reelin's role in multiple sclerosis suggests that modulating its levels could impact immune system function and neuroinflammation. However, specific drug development efforts focusing solely on Reelin as a therapeutic target are still in the early stages, and further research is needed to understand its potential fully.

Newly Identified Genetic Variant Protects Against Alzheimer’s
Harvard Medical School](https://hms.harvard.edu/news/newly-identified-genetic-variant-protects-against-alzheimers)

Reelin' in a new treatment for multiple sclerosis |
ScienceDaily](https://www.sciencedaily.com/releases/2020/08/200812161329.htm).

Depletion in the Entorhinal Cortex of Human Amyloid Precursor Protein Transgenic Mice and Humans with Alzheimer's Disease |
Journal of Neuroscience](https://www.jneurosci.org/content/27/11/2727).