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H2R

Re: HyperPhoenix1 post# 940

Thursday, 07/11/2024 11:30:40 PM

Thursday, July 11, 2024 11:30:40 PM

Post# of 948
Hello HyperPhoenix,

Thank you for putting together this work sheet, very appreciated.

The assumptions are taken from the XL :

Number Injections, 2024
France 1,032,783 Based FrenchHealth Database (2016) plus market growth
Europe 6,905,772 Pro Rata based on the french propulation vs EC
UK 1,032,783 UK has same population than France
USA 9,139,783 I used the ratio of treated patients (US/Europe) according to OTLK ppt



Russ Trenary talked about 2.8M injections of bevacizumab in the EU, and 3.5M in the US. That is what I believe OTLK's target market is, provided US approval.

Is your overall assumption that OTLK is targeting the entire market, including all other therapies and the number of injections is the above? Or ONS-5010 will capture more than the current Wet AMD?

I am optimistic about the future of OTLK and the PPS (see my simple/back of the envelope aspirational revenue target). I want to better understand where you are coming from.

Thank you!

Best of luck with your investments!
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