SRPT decisions and alzheimers decisions strongly suggest that FDA has moved too far toward ‘one leader can overrule all staff’ decision model. Even Musk, in SpaceX decision to move to a steel Starship, had to work very hard to convince his staff. He did not just overrule them, although he absolutely could have. (For those not aware… the fact that it’s steel has now turned out to be immensely important/good)
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