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Post# of 251654
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Re: DewDiligence post# 251485

Wednesday, 04/17/2024 5:09:48 PM

Wednesday, April 17, 2024 5:09:48 PM

Post# of 251654
I believe its entirely or almost entirely due to the actual weight loss. The same phenomenon was seen in the bariatric surgery literature with similar results and seen across the board for different surgical techniques (slight exception with Lap Band showing less weight loss and less AHI reduction). Blinding is of course difficult with bariatric surgery and many of these are uncontrolled studies. Other weight loss drugs have also seen good OSA data. Though results were pretty much a foregone conclusion, the main positive for the GLP-1's is that this data will help to get insurance to cover patients who do not have DM/hyperglycemia

Here's a review
https://www.sciencedirect.com/science/article/pii/S217351151630046X?via%3Dihub

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