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Post# of 251670
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Re: Whalatane post# 251416

Sunday, 04/07/2024 12:24:36 AM

Sunday, April 07, 2024 12:24:36 AM

Post# of 251670
OCUL Glaucoma

FWIW - both glaucoma inserts on the market, the second having just been approved, have a label restriction disallowing use more than once in an eye. For at least Durysta this was not the original plan; it just showed up in the later/bigger trials that repeated use showed problems. My point is that this was not obvious in the earlier/smaller trials that are more like this OCUL one, and I haven’t yet seen strong data on what small trial, single use proxies accurately predict that reuse risk in the later ph3.

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