EFTR—(-82%)—reports disastrous phase-2 data for Tomivosertib as addend to Keytruda in first-line NSCLC: https://finance.yahoo.com/news/effector-therapeutics-announces-topline-results-123000557.html The two-sided p value for PFS, based on a stratified log rank test, was 0.21, which did not meet the pre-specified threshold… Overall survival results remain immature, however no trend favoring tomivosertib was observed. There were 67% Grade 3 or higher treatment emergent adverse events in the tomivosertib plus pembrolizumab arm versus 37% in the placebo plus pembrolizumab arm.