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Re: bUrRpPPP! post# 250494

Thursday, 04/04/2024 4:49:33 PM

Thursday, April 04, 2024 4:49:33 PM

Post# of 251872
EFTR—(-82%)—reports disastrous phase-2 data for Tomivosertib as addend to Keytruda in first-line NSCLC:

https://finance.yahoo.com/news/effector-therapeutics-announces-topline-results-123000557.html

The two-sided p value for PFS, based on a stratified log rank test, was 0.21, which did not meet the pre-specified threshold… Overall survival results remain immature, however no trend favoring tomivosertib was observed.

There were 67% Grade 3 or higher treatment emergent adverse events in the tomivosertib plus pembrolizumab arm versus 37% in the placebo plus pembrolizumab arm.


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