TRACON Pharmaceuticals Inc (TCON)

[axelvento]

With a float of 26 million shares and a market cap of $23 million, TRACON operates within the realm of oncology research and development. Envafolimab, one of TRACON’s key assets, has garnered both Fast Track Designation and Orphan Drug Designation. Envafolimab, a novel PD-L1 antibody, is administered via subcutaneous injection, offering a convenient treatment approach.

The pivotal Phase 3 trial for Envafolimab, known as ENVASARC, is anticipated to provide updated safety and efficacy data by the end of the first quarter of 2024, with final data expected in the second half of the same year. The study design, presented at the American Society of Clinical Oncology (ASCO) in the previous year, outlines primary endpoints focused on objective response rate (ORR) confirmed by independent central review. The trial aims to assess Envafolimab’s efficacy, particularly in refractory undifferentiated pleomorphic sarcoma (UPS) or myxofibrosarcoma (MFS) patients, with an ORR confirmed by BICR with 9/80 objective responses needed to exclude the known < 5% ORR of pazopanib, the only agent approved for patients with refractory UPS or MFS.