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Re: djjazzyjeff post# 230497

Saturday, 03/02/2024 6:12:16 PM

Saturday, March 02, 2024 6:12:16 PM

Post# of 232959
HIV chronic immune activation and inflammation study? Dont cheap drugs bought at the pharmacy like Prednisolone and Chloroquine/Hydroxychloroquine already have that market cornered?

HIV-Related Immune Activation and Inflammation: Current Understanding and Strategies

4.1.1. Prednisolone In 2012, Kasang et al. reported that prednisolone has beneficial effects on immunological correlates of HIV disease progression in untreated HIV-infected patients (CD38+CD8+%, CD38+CD4+%, sCD14, and LPS-binding protein (LBP)), but no additional beneficial effects in patients treated with ART [76]

4.1.2. Chloroquine/Hydroxychloroquine (CQ/HCQ) Agents with immunosuppressive properties were first tried in PLWH in 1998, which could both break the vicious cycle that leads to the slow attrition of the lymphocyte pools [81]. Both CQ and HCQ have been widely used in treating autoimmune conditions, such as lupus and arthritis, and they could also suppress the HIV-1 replication in patients [82].
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494587/


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