Biotech Values

[jbog]

Mufaso

What was your impression of the 14% to 20% discontinuation for the two upper doses at 13 weeks. What am I missing? They did decent titration.



Patients treated with VK2735 were titrated to final doses as indicated:
2.5 mg cohort = 2.5 x 13 weeks;
5 mg cohort = 2.5 mg x 3 wks, 5 mg x 10 wks;
10 mg cohort = 2.5 mg x 3 wks, 5 mg x 3 wks, 7.5 mg x 3 wks, 10 mg x 4 wks;
15 mg cohort = 5 mg x 3 wks, 7.5 mg x 3 wks, 10 mg x 3 wks, 15 mg x 4 wks