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Re: jondoeuk post# 229

Monday, 02/12/2024 6:50:08 PM

Monday, February 12, 2024 6:50:08 PM

Post# of 249
Question: Given the results published thus far on the TSC-100 / TSC-101 trial, and knowing this is second line treatment post HCT, as per the approved trial NCT05473910;

When would TSC-100 / TSC-101 go into a first line treatment scenario trial?

Is that even possible in the current trial or would a new trial (IND) need to be initiated / approved.

When analysing the donor chimerism data on the February Presentation - slide 14 and additional abstract results...

https://ir.tscan.com/static-files/1d066354-1ed3-4f4f-b97b-28806d9da9f5

...it demonstrates imo, that TSC-100 / TSC-101 should be first line treatment.
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