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Alias Born 02/15/2023

Re: iwfal post# 245495

Monday, 02/05/2024 11:45:56 PM

Monday, February 05, 2024 11:45:56 PM

Post# of 251945
Have you seen the final trial design? It’s just one cohort. The 2L setting was eliminated because of uptake of Trodelvy in that setting. The trial is overenrolled and seems adequately powered to me. There wasn’t a material difference in 1L vs 2L efficacy in the P2. It was numerically lower but very small numbers. The bigger variable is the larger PDL (-) population in the P3

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