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Sunday, 02/04/2024 7:25:57 PM

Sunday, February 04, 2024 7:25:57 PM

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(OT) oNKo-innate is a discovery-stage biotech company dedicated to target identification and preclinical IO (drug) development.

In this, the functional genomics and target discovery team have used their platform to perform enrichment screens in primary human NK cells, identifying novel IL-15 axis regulators that contribute to survival and persistence. Phenotypic screens similarly revealed regulators of NK cell cytotoxicity and interferon gamma production. By validating these targets, the team has demonstrated that they are able to regulate various aspects of NK and CAR-NK cell function.

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