EyePoint Pharmaceuticals Inc (EYPT)

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Prevalence of AMD

Approximately 20 million people in the United States have AMD, and nearly 1.5 million Americans have the advanced form of the disease.2,5

About 200,000 new cases of wet AMD are diagnosed each year in North America.6

Between 2010 and 2050, the estimated number of people with AMD will more than double from 2.1 million to 5.4 million.7

[url]https://www.gene.com/patients/disease-education/amd-fact-sheet#:~:text=Wet%20AMD%20accounts%20for%20approximately,90%20percent%20of%20legal%20blindness.&text=Wet%2C%20or%20neovascular%2C%20AMD%20is,rapid%20and%20severe%20vision%20loss.
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References

1 National Eye Institute. Age-related macular degeneration: What You Should Know. National Eye Institute:
NIH publication 03-2294. Available at: https://www.nei.nih.gov/learn-about-eye-health/eye-conditions-and-diseases/age-related-macular-degeneration#section-id-7325. Accessed February 3, 2023.

2 BrightFocus Foundation. Age-Related Macular Degeneration: Facts & Figures. Available at: https://www.brightfocus.org/macular/article/age-related-macular-facts-figures. Accessed February 3, 2023.

3 Jager RD, Mieler WF, Miller JW. Age-Related macular degeneration. New England Journal of Medicine. 2008; 358:2606-2617

4 American Academy of Ophthalmology. What is Macular Degeneration?. Available at: https://www.aao.org/eye-health/diseases/amd-macular-degeneration. Accessed February 3, 2023.

5 JAMA Ophthalmology. Original Investigation: Prevalence of Age-Related Macular Degeneration in the US in 2019. Available at: https://jamanetwork.com/journals/jamaophthalmology/article-abstract/2797921. Accessed February 3, 2023.

6 Maguire MG. Comparing treatments for age-related macular degeneration: safety, effectiveness and cost. Issue Brief. 2012;17(8). Leonard Davis Institute of Health Economics. Accessed February 7, 2020. https://ldi.upenn.edu/wp-content/uploads/archive/pdf/Issue%20Brief%2017_8.pdf

7 National Eye Institute.Age-Related Macular Degeneration: NEI Looks Ahead. States. Available at: https://medialibrary.nei.nih.gov/search?keywords=&f%5B0%5D=category%3A4#/media/1777. Accessed February 3, 2023.

8 BrightFocus Foundation. Macular Degeneration: Essential Facts. Available at: https://www.brightfocus.org/macular/news/macular-essential-facts. Accessed February 3, 2023.