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Re: drkazmd65 post# 146171

Tuesday, 01/30/2024 7:38:24 AM

Tuesday, January 30, 2024 7:38:24 AM

Post# of 146201
"The pre-clinical studies already pretty much established that point"
Which point? Certainly not that NV-387 DOES NOT have significant dose-limiting toxicities.
The Maximum Tolerable Dose in rats was established in pre-clinical trials.

"That wasn't actually the point of the Phase I trails?"
I guess that's my mistake. I thought the attempt to determine the MTD in humans was a basic goal of any Phase 1 trial.


Let's not forget where this issue became an issue.
The Company said that in contrast to its drug "most known antiviral drugs have significant dose-limiting toxicities."
I thought it was reasonable to assume from that statement that NV-387 DOES NOT have significant dose-limiting toxicities and you're telling me that establishing that wasn't a point of the trials.
Then why the comparison statement?

note: my passive aggressive comment was based on your "Have a good afternoon". My apologies if you were being sincere.

No matter what it is or who commenced it, I'm against it!
....Groucho

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