RMB. Happy , healthy and prosperous new year to you and your family also .
Re UNCY ...( while its fresh )
Recent heavy vol in a holiday week indicates ( to me at least ) a fund like Vivo Capital is increasing their stake.
Vivo is in Palo Alto not far from where UNCY is located.
Re serum phosphorus . High serum phosphorus levels in dialysis patients causes calcification in coronary arteries etc ...so Nephrologists always want their patients to control phosphorus levels. Problem is that most of the current binders to do that are large pills that often need to be chewed following meal ...like chewing chalk I'm told. So patients hate them , compliance is poor . Most don't meet their goals.
ARDX developed Xphozah which is 2 small pills a day . Problems with it is that most experience diarrhea trying to transition to it and Co want close to $3,000 a mth for the frug. At Tier 5 pharmacy level the patient needs to pay close to $1,000 a mth copay ......which will be difficult as most / many on dialysis have limited income due to the fact they are hooked up to a dialysis machine 4 hrs a day ...3 times a week .
UNCY's drug OLC is 1 small pill with each meal that can be swallowed ( not chewed ) , is an improved / condensed version of an existing binder ( Fosrenol ) that my wife currently prescribes to some of her patients .
OLC is the bio equivalent to Fosrenol however the FDA wants a final small trial with dialysis patients as an earlier trial has showed that altho the adverse events were the same in both drugs ...there were more of them in the earlier OLC trial compared to Fosrenol data .
So the final trial is enrolling and the results should be known by end of Q2 2024
My investment is a spec on this trial .
Its high risk .
If the trial is seen as a failure with low prospects of ever supporting FDA approval of this drug ......stock will tank .
If the trial is a success ...the Co will almost immediately raise funds .
I'm hoping for a SLNO like outcome . Vivo Capital is one of the largest shareholders in SLNO . I owned it at around $2 and sold it when it hit $20 on the trial read out ...and declared myself a genius ....however ...:--(
Stock is now trading around $40 and Vivo still owns it
Kiwi
