Immunovant Inc (IMVT)

[MiamiGent]

I'm taking IMVT here @ $40.02 +3.839 (+10.61%)
Looking for a couple of gentlemanly dollars
As of Dec-21-20239:49:07 AM ET

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The News
Autoimmune Disease Player Immunovant's Investigational Drug For Immune System Disorder Shows Response Rates Of Over 50%
BENZINGA
Immunovant Inc (IMVT.NaE) , on Thursday, released the results from the initial cohort of patients in an ongoing 24-week Phase 2 trial of batoclimab in patients with Graves' disease.

Graves' disease is an immune system disorder that results in the overproduction of thyroid hormones (hyperthyroidism).

The company says the results show that batoclimab meaningfully exceeded 50% response rates.

Consistent with studies of batoclimab in other indications, 680 mg administered subcutaneously (SC) in the initial cohort demonstrated an IgG reduction of up to 87%, with a mean IgG reduction of 81% after 12 weeks of treatment.

The 340 mg IgG reductions were lower. A similar dose response was observed for anti-TSHR autoantibodies, with deeper reductions observed following treatment with 680 mg of SC batoclimab compared to 340 mg of SC batoclimab.

In addition, numerically higher responses were observed following treatment with 680 mg of batoclimab across a range of clinical parameters compared to treatment with 340 mg of batoclimab.

Batoclimab was generally well tolerated, with no new safety signals observed in the initial data set.