V116 is 21-valent—i.e. it contains 13 of the 20 serotypes in PFE’s Prevnar-20 and 8 new serotypes. By simple arithmetic, V116 lacks 7 of the serotypes in Prevnar-20, but MRK contends that those 7 serotypes are less influential than the 8 new serotypes.
PFE currently has a >90% share of the adult market for pneumococcal vaccines, but V116 will presumably get MRK back in the game. See #msg-172452293 and #msg-166441188 for related info.
Note: V116 is a distinct product from MRK’s Vaxneuvance (a/k/a V114).
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