Monday, December 04, 2023 10:52:17 AM
I say that for two new reasons. First, Novavax announced approval of their standard vaccine in South Korea just days ago.
https://ir.novavax.com/press-releases/Novavaxs-Updated-COVID-19-Vaccine-Receives-Emergency-Use-Authorization-in-the-Republic-of-Korea
And we know that S. Korea conducted a safety trial of Humanigen's lenzilumab some time ago.
https://ir.humanigen.com/English/news/news-details/2021/Humanigens-Partner-in-South-Korea-Receives-Ministry-of-Food-and-Drug-Safety-MFDS-Approval-to-Conduct-Phase-1-Study-of-Lenzilumab/default.aspx
In addition, the WHO's Emergency Use Listing (EUL) approval of the standard Novavax vaccine was based on non-clinical data.
However, in regards to Novavax's prototype vaccine, "In clinical trials, the most common adverse reactions associated with Novavax's prototype COVID-19 vaccine (NVX-CoV2373) included headache, nausea or vomiting, muscle pain, joint pain, injection site tenderness, injection site pain, fatigue and malaise." It would likely have been the prototype vaccine that used lenz as an adjuvant.
It would be very exciting to see news in this regard, if my assumption about incorporating lenz in the prototype vaccine is correct.
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