NeuroSense Therapeutics Ltd (NRSN)

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NeuroSense Therapeutics to Present at Upcoming U.S. and European ALS Conferences NeuroSense Therapeutics

09 Nov, 2023, 09:00 ET

https://www.prnewswire.com/news-releases/neurosense-therapeutics-to-present-at-upcoming-us-and-european-als-conferences-301983397.html


- Last patient completed the double-blind segment of PARADIGM, a Phase 2b ALS Trial

- Clinical efficacy top-line results from PARADIGM expected in December 2023

CAMBRIDGE, Mass., Nov. 9, 2023 /PRNewswire/ -- NeuroSense Therapeutics Ltd. (Nasdaq: NRSN) ("NeuroSense"), a company developing treatments for severe neurodegenerative diseases, today announced scientific presentations at three upcoming conferences.

Neuroscience 2023

Mr. Nitai Kerem, NeuroSense's Scientific Project Manager, will present a poster on NeuroSense's latest biomarker data at Neuroscience 2023, the Society of Neuroscience's annual conference. This is the largest U.S. Neuroscience conference, bringing together scientists and physicians devoted to understanding the brain and the nervous system. The conference will be held in Washington D.C. on November 11th-15th, 2023.

ALS ONE's 6th Annual ALS Research Symposium

Dr. Shiran Zimri, VP of R&D at NeuroSense, will present the Company's latest clinical updates and findings in her talk titled "Shifting the Paradigm - A Biomarker Driven Approach for Studying Amyotrophic Lateral Sclerosis (ALS) Therapy Activity" at ALS ONE's 6th Annual ALS Research Symposium, to be held virtually on November 16th-17th, and 20th 2023. In addition to NeuroSense being a sponsor of this year's conference, this marks the fourth year NeuroSense will present at ALS ONE's symposium.

With a focus on the Company's Phase 2b PARADIGM PrimeC study, Dr. Zimri will present key elements of PrimeC's development program. The last patient has completed the double-blind segment of PARADIGM, with clinical efficacy results (secondary endpoints) expected in December 2023.

The 34th International Symposium on ALS/MND

Dr. Shiran Zimri and Dr. Ferenc Tracik, NeuroSense's Chief Medical Officer, will present a poster at the 34th International Symposium on ALS/MND, which brings together leading ALS and motor neuron disease (MND) experts, European patient advocacy groups, and ALS foundations, on December 6th-9th, 2023 in Basel, Switzerland.

"We believe NeuroSense's highly innovative approach of using biomarkers as a primary efficacy endpoint in our Phase 2b PARADIGM study will further elucidate the biological activity of PrimeC and help us to better understand the effect on people living with ALS," said Dr. Zimri. "We are excited to soon begin sharing the initial results of the double-blind segment of our Phase 2b trial to determine our drug's impact on efficacy."

About PARADIGM

NeuroSense's Phase 2b PARADIGM trial evaluating PrimeC's efficacy, as well as safety and tolerability, in people living with ALS. The study is randomized 69 people living with ALS in a 2:1 ratio to receive PrimeC or placebo, respectively. Primary endpoints of the study include assessment of ALS biomarkers, evaluation of clinical efficacy, improvement in quality of life, as well as safety and tolerability.