Jaguar Health Inc (JAGX)

[oldstocks]

M D Anderson Cancer Center is # for cancer care
https://www.mdanderson.org/1 in the nation
The surgeon that operated on my cancer came from M D Anderson Cancer Center in Texas and transferred to Orlando where he operated on me.
I am a live! Some of the best come from M D Anderson Cancer Center.

Jaguar Health Napo Pharmaceuticals Phase 3 Affiliation with M D Anderson Cancer Center has my attention.

NP 303-102
https://clinicaltrials.gov/study/NCT04538625?tab=history&a=8
Prophylaxis of Diarrhea in Adult Cancer Patients Receiving Targeted Cancer Therapy
A Phase 3 Multicenter, Randomized, Double-blind Placebo-controlled Trial Evaluating Crofelemer for the Prophylaxis of Diarrhea in Adult Patients With Solid Tumors Receiving Targeted-cancer Therapies With or Without Standard Chemotherapy
• Name
Pablo Okhuysen, MD
Role
Principal Investigator
Affiliation
M.D. Anderson Cancer Center
https://www.mdanderson.org/patients-family/search-results.v2.html?q=Pablo%20Okhuysen#_
Pablo C. Okhuysen, M.D., FACP, FIDSA, Department of Infectious Diseases, Infection Control, and Employee Health, Division of Internal Medicine
ON TARGET: A Phase 3 multicenter, randomized, double-blind placebo-controlled trial evaluating crofelemer for the prophylaxis of diarrhea in adult patients with solid tumors receiving targeted-cancer therapies with or without standard chemotherapy regimen
A 24-week, (two 12-week stages), randomized, placebo-controlled, double-blind study to evaluate the safety and efficacy of crofelemer in providing prophylaxis of diarrhea in adult patients with solid tumors treated with targeted cancer therapy-containing treatment regimens. Diarrhea grading will be done according to the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) version 5.0. Patients will be randomized 1:1 to placebo or crofelemer and will be stratified by the type of targeted cancer therapy and the tumor type. Placebo and/or crofelemer will be dispensed at Visit 1/Day 1 with the concurrent start of the targeted cancer therapy regimen. The initial Stage I double-blind placebo-controlled primary treatment phase will occur over a 12-week period to accommodate approximately 3 cycle chemotherapy cancer treatment dosing-cycles. The Primary and Secondary Endpoints will be analyzed after the last patient last visit (LPLV) of Stage I. After completing the Stage I double-blind, placebo-controlled primary treatment phase, the subjects will have the option to remain on their assigned treatment arm and reconsented to enter into the Stage II extension phase. Reconsent will be required to enter into Stage II. For subjects who do not reconsent, visit 5 will be the last study visit.


• Name
Pravin Chaturvedi, PhD
Dr. Pravin Chaturvedi is the Chairman of the Scientific Advisory Board for Napo Pharmaceuticals and is the CEO for IndUS and Oceanyx Pharmaceuticals. He is an experienced drug developer and biotech entrepreneur. Previously he was the CEO of Pivot and Scion Pharmaceuticals; and was the Head of Lead Evaluation at Vertex and was in Product Development groups at Alkermes and Parke-Davis/Warner-Lambert (Pfizer). Over his career, he has participated in the successful development of several new drugs for the treatment of CNS, viral and gastrointestinal disorders. Dr. Chaturvedi serves on the boards of Oceanyx, IndUS, Cellanyx, FuelEd Schools and Sindu Research Laboratories; and previously served on the boards of Pivot, Scion, Bach Pharma, PRADAN USA, Sindu Pharmaceuticals and TiE Boston. He is an adjunct faculty member at Georgetown Medical School and serves on several advisory boards. He holds a Ph.D. in Pharmaceutical Sciences from West Virginia University.
https://bostonbiotechnologysummit.com/program/speakers/pravin-r-chaturvedi-ph-d/
Role
Study Chair
Affiliation
Napo Pharmaceuticals
https://www.biospace.com/article/releases/jaguar-health-announces-appointment-of-pravin-chaturvedi-ph-d-as-chief-scientific-officer/
Locations:
• Prescott, Arizona, United States, 86314
Facility:
Arizona Oncology Associates PC - HAL
• Anaheim, California, United States, 92801
Facility:
Pacific Cancer Medical Center Inc
• Corona, California, United States, 92882
Facility:
The Oncology Institute of Hope and Innovation
• Glendale, California, United States, 91204
Facility:
The Oncology Institute of Hope and Innovation
• Whittier, California, United States, 90602
Facility:
PIH Health Whittier Hospital
• Lafayette, Colorado, United States, 80218
Facility:
SCL Health Research Institute
• Aventura, Florida, United States, 33180
Facility:
GenesisCare USA
• Palm Bay, Florida, United States, 32909
Facility:
Cancer Care Centers of Brevard, Inc.
• Plantation, Florida, United States, 33322
Facility:
BRCR Global
• Saint Petersburg, Florida, United States, 33710
Facility:
Advanced Research Institute
• Bethesda, Maryland, United States, 20817
Facility:
American Oncology Partners of Maryland
• Minneapolis, Minnesota, United States, 55404
Facility:
Minnesota Oncology Hematology, P.A.
• Omaha, Nebraska, United States, 68114
Facility:
Nebraska Methodist Hospital
• Bronx, New York, United States, 10461
Facility:
Jacobi Medical Center
• Port Jefferson Station, New York, United States, 11776
Facility:
North Shore Hematology Oncology Associates dba New York Cancer and Blood Specialists
• Canton, Ohio, United States, 44718
Facility:
Gabrail Cancer Research
• Portland, Oregon, United States, 97239
Facility:
Oregon Health & Science University (OHSU) Knight Cancer Institute
• Germantown, Tennessee, United States, 38138
Facility:
The West Clinic Research
• Denison, Texas, United States, 75020
Facility:
Texas Oncology - Denison
• Flower Mound, Texas, United States, 75028
Facility:
Texas Oncology, P.A. - Flower Mound
• Houston, Texas, United States, 77030
Facility:
MD Anderson Cancer Center
• New Braunfels, Texas, United States, 78130
Facility:
Texas Oncology - New Braunfels
• Plano, Texas, United States, 75075-7787
Facility:
Texas Oncology - Plano East
• Webster, Texas, United States, 77598
Facility:
Texas Oncology - Gulf Coast
• Fairfax, Virginia, United States, 22031
Facility:
Inova Schar Cancer Institute
• Winchester, Virginia, United States, 22601
Facility:
Shenandoah Oncology Associates
• Tacoma, Washington, United States, 98405
Facility:
MultiCare Institute for Research and Innovation
• Buenos Aires, Argentina, 1414
Facility:
Fleischer Medical Center
• Buenos Aires, Argentina, C1019ABS
Facility:
Medical Center Austral
• Buenos Aires, Argentina
Facility:
Buenos Aires British Hospital
• Córdoba, Argentina
Facility:
Cordoba Oncology Institute (IONC)
• Paraná, Argentina, 3100
Facility:
Center of Nuclear and Molecular Medicine of Entre Rios (CEMENER)
• Salta, Argentina
Facility:
CEDIT Diagnostic and Treatment Center
• Santa Fe, Argentina, S3000FFV
Facility:
Isis Specialized Clinic
• Tucuman, Argentina, 4000
Facility:
9 of July Sanatorium
• Tbilisi, Georgia, 0112
Facility:
LLC "Todua Clinic"
• Tbilisi, Georgia, 0159
Facility:
Archangel St. Michael Multiprofile Clinical Hospital LTD
• Tbilisi, Georgia, 0159
Facility:
JSC K. Eristavi National Center of Experimental and Clinical Surgery
• Tbilisi, Georgia, 0172
Facility:
Malkhaz Katsiashvili Multiprofile Emergency Medicine Center LLC
• Tbilisi, Georgia, 0186
Facility:
LTD Caucasus Medical Centre
• Belgrade, Serbia, 11 080
Facility:
Clinical Hospital Center Bezanijska Kosa
• Belgrade, Serbia, 11000
Facility:
National Cancer Research Center
• Kragujevac, Serbia, 34 000
Facility:
University Clinical Center Kragujevac
• Nis, Serbia, 18 000
Facility:
University Clinical Center Nis
• Sremska Kamenica, Serbia, 21204
Facility:
Institute of Pulmonary Diseases of Vojvodina
• Sremska Kamenica, Serbia, 21204
Facility:
Oncology Institute of Vojvodina (IOV)
• Changhua, Taiwan, 500
Facility:
Changhua Christian Hospital
• Kaohsiung, Taiwan
Facility:
Kaohsiung Chang Gung Memorial Hospital
• Taichung, Taiwan, 404332
Facility:
China Medical University Hospital
• Tainan, Taiwan, 736402
Facility:
Chi Mei Medical Center - LiouYing Branch
• Taipei, Taiwan, 100226
Facility:
National Taiwan University Hospital
• Taipei, Taiwan, 112201
Facility:
Taipei Veterans General Hospital