Innovation Pharmaceuticals Inc (IPIX)

[farrell90]

Fungal disease is becoming more common

"Annually, over 150 million severe cases of fungal infections occur worldwide, resulting in approximately 1.7 million deaths per year. Alarmingly, these numbers are continuously on the rise with a number of social and medical developments during the past decades that have abetted the spread of fungal infections. Additionally, the long-term therapeutic application and prophylactic use of antifungal drugs in high-risk patients have promoted the emergence of (multi)drug-resistant fungi, including the extremely virulent strain Candida auris. Hence, fungal infections are already a global threat that is becoming increasingly severe. In this article, we underline the importance of more and effective research to counteract fungal infections and their consequences."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278517/

"Climate changes in temperature and rainfall are enabling the spread of certain fungal lung diseases beyond their traditional geographic hot spots in the United States, and doctors commonly miss the diagnosis."

https://www.upi.com/Health_News/2022/11/21/fungal-infections-climate-change-study/1171669045633/

As temperatures rise, fungi can develop tolerance for warmer environments — including the bodies of humans and other mammals, whose naturally high temperatures typically keep most fungal pathogens at bay. Over time, humans may lose resistance to these climate-adapting fungi and become more vulnerable to infections. Some researchers think this is what is happening with C. auris.

https://grist.org/health/candida-auris-infections-spread-us-climate-change/

GLTA Farrell