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Re: PJ007 post# 398590

Saturday, 07/29/2023 4:40:28 PM

Saturday, July 29, 2023 4:40:28 PM

Post# of 402685
"In summary, we identified five molecules,
Hayatinine, Bedaquiline, Brilacidin, Curine, and MMV688271 that completely blocked invasion/schizont rupture at IC50"

Thanks for posting. This finding is consistent with Polymedix's lab findings that some of their small molecule mimetic of defensin, a type of host defense proteins/peptides (HDPs) or antimicrobial peptides had an inhibitory affect against malaria.

This study confirms Brilacidin also possesses antimalarial inhibitory effects. Brilacidin is truly a multifaceted compound with proven antibacterial,antiviral,antifungal and now antiparasitic antimalarial effects.

GLTA Farrell
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