Novocure Ltd (NVCR)

[dstock07734]

jondoeuk,

Like Dr. Bala suggested before, you need to update your knowledge structure. English is your native language. Right? Read carefully what Dr. Stupp wrote. Where did Dr. Stupp explicitly mention that FDA should not grant approval to DCVax-L? As a matter of fact, in the past two years, Dr. Stupp has been helping NWBO to get the approval.

The results are intriguing; yet, it remains to be demonstrated that the effect observed is truly due to DCVax rather than a mere reflection of patient selection. There is a strong movement to allow for synthetic controls to replace randomized trials and limit the number of patients to be treated as controls, particularly in diseases like glioblastoma, where better treatments are urgently needed and progress has been slow. But, what magnitude of an effect do we want to see by accepting historical external controls in lieu of randomized trials for proof of efficacy? Being too stringent carries the risk of rejecting a potentially effective treatment strategy that could ultimately unfold its full potential if used in an optimized context or in combination, whereas criteria that are too relaxed will expose patients to ineffective treatments, toxicity, and costs and will ultimately hamper the development of more effective innovative therapies. Timely and appropriate trial design with meaningful and reproducible endpoints, efficient enrollment, and adequate funding remain the most efficient way to provide patients access to better treatments with proven efficacy, approved and reimbursed.

BTW, next time you posted something. Make sure it is working.
https://www.practiceupdate.com/content/2022-top-story-in-oncology-dcvax-in-patients-with-newly-diagnosed-and-recurrent-glioblastoma/143631

Placebo has better OS. Are you kidding me? You must have been brainwashed by AF.
Among1366 GBM patients from the external control group, none made for the 5th year. Some of the patients came from the trial that Dr. Stupp was the PI. Dr. Liau alone has 62 patients still alive. Ask any neurosurgeon you know: has she/he heard of this type of miracle?