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jondoeuk

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jondoeuk

Re: NY1972 post# 296

Monday, 06/12/2023 7:01:54 PM

Monday, June 12, 2023 7:01:54 PM

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If they could upend auto BCMA and/or CD19 CARs, I think it might.

As for HER2, that is partnered with Ono Pharma, a CAR-T, with several edits (CAR uses a CD28zeta mutant that contains one instead of all three iTAMs, TCR knockout, high-affinity and non-cleavable CD16 receptor, IL-7 receptor, CD38 knockout, TGF-R 'switch' receptor, and CXCR2 chemokine receptor).
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