Aptose Biosciences Inc (APTO): Preclinical drug formulation is differen...

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Re: Tartiaboy post# 396

Wednesday, 06/07/2023 11:34:54 AM

Wednesday, June 07, 2023 11:34:54 AM

Preclinical drug formulation is different from clinical. To me, it looks like they didn't analyze solubility of G1 formulation in GI tract environment although it is a simple test. I call it negligence which resulted in waste of time and resources. Had they done this test, they wouldn't have "reasonable expectations". Combinations at the beginning with precipitating drug? Not sure it is a good strategy.

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