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Friday, 05/26/2023 5:41:34 PM

Friday, May 26, 2023 5:41:34 PM

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''During the development of our clonal neoantigen T cell therapy (cNeT) for treatment of solid tumours, we identified and screened circa 10,000 clonal neoantigens for T cell reactivity using cells grown from tumour infiltrating lymphocytes. Using this unique data, we developed and validated an AI method for predicting neoantigen immunogenicity, significantly outperforming existing tools. This technology has broad applicability for optimising target selection across all types of personalised neoantigen therapies.''

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