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Re: Mufaso post# 247105

Monday, 05/22/2023 4:13:59 PM

Monday, May 22, 2023 4:13:59 PM

Post# of 251709
HEPA—After listening to the CC, I’m not impressed with the dataset reported today. One notable blemish is the lack of a typical dose response—i.e. the 150mg dose performed considerably worse than either the 75mg or 225mg doses.

The trial’s primary endpoint and a few of the secondary endpoints are experimental (non-validated) biomarkers, so it’s hard to say how much predictive value they will have.

Bottom line: I will keep on open mind, but I saw nothing today to convince me that investors should take the company’s NASH program seriously.

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