Remdesivir also showed clinical efficacy despite no effect on viral loads in the nasopharynx in the outpatient setting. Enta mentioned this on the call but here’s the link for reference.
Thanks dewophile. It makes you wonder why nasal viral RNA levels are used as a metric of drug anti-Covid efficacy. I don't recall ENTA mentioning that in the CC. Thanks.
FWIW, the patients in the Remdesivir trial were older than in the ENTA and Shionogi studies, and were high risk having at least one risk factor .
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