Tuesday, May 02, 2023 9:43:24 AM
People with wet age-related macular degeneration must take frequent eye injections of biologic drugs like Lucentis and Eylea to slow the vision loss they experience. Drugmakers have sought to reduce the frequency of those injections to help patients as well as ophthalmologists seeking to free up staff and office resources. Meanwhile, insurers — primarily Medicare in the U.S. — have been looking to reduce the costs of paying for physician services.
The Food and Drug Administration recommends injecting Lucentis once a month, although patients can go with less frequent appointments if they’re willing to sacrifice some efficacy. Eylea, on the other hand, has similar effectiveness when taken every eight weeks after an initial dosing period of once every four weeks.
Vabysmo reduced dosing even further, to once every four months. Its annual list price of $6,570 during that maintenance phase, or $2,190 a shot, is competitive with Lucentis biosimilars, which cost around $1,000 a shot. Eylea biosimilars are expected to enter sometime this year or next.
Vabysmo’s strong launch puts pressure on Regeneron, which relies on Eylea for a bulk of its sales. But Regeneron aims to soon win U.S. approval of a high-dose version that could blunt competition.
Analysts at RBC Capital Markets expect Vabsymo’s market share to grow, but wrote in a note to clients that “the window of opportunity for Vabysmo to make significant competitive inroads to Eylea franchise may be narrowing” with the high-dose Eylea formulation coming.
Recent OTLK News
- Outlook Therapeutics® to Participate in the Virtual Investor Closing Bell Series • GlobeNewswire Inc. • 09/16/2024 12:05:00 PM
- Outlook Therapeutics® Participates in the 2nd Annual Chardan Virtual Ophthalmology Conference Series • GlobeNewswire Inc. • 09/13/2024 01:05:00 PM
- Outlook Therapeutics® Announces Completion of Enrollment in NORSE EIGHT Clinical Trial • GlobeNewswire Inc. • 09/04/2024 12:35:00 PM
- Outlook Therapeutics® to Present at the H.C. Wainwright 26th Annual Global Investment Conference • GlobeNewswire Inc. • 09/03/2024 12:45:00 PM
- Form S-8 - Securities to be offered to employees in employee benefit plans • Edgar (US Regulatory) • 08/14/2024 08:55:20 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/14/2024 08:15:28 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 08/14/2024 11:48:51 AM
- Outlook Therapeutics® Reports Financial Results for Third Quarter Fiscal Year 2024 and Provides Corporate Update • GlobeNewswire Inc. • 08/14/2024 11:05:00 AM
- Outlook Therapeutics® to Present at the H.C. Wainwright 4th Annual Ophthalmology Virtual Conference • GlobeNewswire Inc. • 08/12/2024 01:05:00 PM
- Outlook Therapeutics® to Report Financial Results for Third Quarter Fiscal Year 2024 on August 14, 2024 and Host Quarterly Conference Call and Webcast • GlobeNewswire Inc. • 08/07/2024 12:35:00 PM
- Outlook Therapeutics® to Present at the BTIG Virtual Biotechnology Conference 2024 • GlobeNewswire Inc. • 07/30/2024 01:10:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 07/08/2024 12:41:41 PM
- Outlook Therapeutics® Announces UK MHRA Marketing Authorization of LYTENAVA™ (bevacizumab gamma) for the Treatment of Wet AMD • GlobeNewswire Inc. • 07/08/2024 12:35:00 PM
- Form PRE 14A - Other preliminary proxy statements • Edgar (US Regulatory) • 06/14/2024 08:10:50 PM
- Outlook Therapeutics® to Present at the Virtual Investor Pitch Conference • GlobeNewswire Inc. • 06/11/2024 01:05:00 PM
- Outlook Therapeutics® Receives European Commission Marketing Authorization for LYTENAVA™ (bevacizumab gamma) for the Treatment of Wet AMD • GlobeNewswire Inc. • 05/28/2024 12:05:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 05/15/2024 09:19:05 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 05/15/2024 09:15:37 PM
- Outlook Therapeutics® Reports Financial Results for Second Quarter Fiscal Year 2024 and Provides Corporate Update • GlobeNewswire Inc. • 05/15/2024 09:00:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 05/13/2024 08:05:33 PM
- Outlook Therapeutics® Announces UK Submission of Marketing Authorization Application (MAA) for ONS-5010 as a Treatment for Wet AMD • GlobeNewswire Inc. • 05/13/2024 12:50:00 PM
- Outlook Therapeutics® to Report Financial Results for Second Quarter Fiscal Year 2024 on May 16, 2024 and Host Inaugural Quarterly Conference Call and Webcast • GlobeNewswire Inc. • 05/09/2024 12:45:00 PM
- Form EFFECT - Notice of Effectiveness • Edgar (US Regulatory) • 05/07/2024 04:15:34 AM
- Form 424B3 - Prospectus [Rule 424(b)(3)] • Edgar (US Regulatory) • 05/06/2024 08:09:46 PM
- Outlook Therapeutics® to Present at the Retina World Congress 2024 • GlobeNewswire Inc. • 05/02/2024 01:05:00 PM
North Bay Resources Commences Operations at Bishop Gold Mill, Inyo County, California; Engages Sabean Group Management Consulting • NBRI • Sep 25, 2024 9:15 AM
CEO David B. Dorwart Anticipates a Bright Future at Good Gaming Inc. Through His Most Recent Shareholder Update • GMER • Sep 25, 2024 8:30 AM
Cannabix Technologies and Omega Laboratories Inc. Advance Marijuana Breathalyzer Technology - Dr. Bruce Goldberger to Present at Society of Forensic Toxicologists Conference • BLOZF • Sep 24, 2024 8:50 AM
Integrated Ventures, Inc Announces Strategic Partnership For GLP-1 (Semaglutide) Procurement Through MedWell USA, LLC. • INTV • Sep 24, 2024 8:45 AM
Avant Technologies Accelerates Creation of AI-Powered Platform to Revolutionize Patient Care • AVAI • Sep 24, 2024 8:00 AM
VHAI - Vocodia Partners with Leading Political Super PACs to Revolutionize Fundraising Efforts • VHAI • Sep 19, 2024 11:48 AM