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Re: frenchbroad post# 397548

Tuesday, 04/25/2023 2:43:25 PM

Tuesday, April 25, 2023 2:43:25 PM

Post# of 402948
"New in vivo data in an A. fumigatus murine fungal keratitis model showed brilacidin reduced fungal burden and disease severity, while also improving corneal thickness compared to control. brilacidin-treated corneas harbored almost no viable fungus, suggesting the compound suppressed fungal proliferation within the cornea. Worldwide, on an annual basis, fungal keratitis affects up to 1.5 million people, of whom 75 percent may lose an eye and/or their sight".

You brought the proof frenchbroad.

More animal model testing planned
"Planned next steps in brilacidin antifungal research include extending in vitro and in vivo testing into additional clinical isolates and animal models, and publishing scientific findings. In collaboration with the NIH/NIAID’s mycology division, brilacidin also is to be screened in multiple fungal species to further characterize its broad-spectrum antifungal activity. Future updates are planned".

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