AC Immune SA (ACIU)

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CEO Andrea Pfeifer about Alzheimer & Parkinson:
(from an interview with german weekly magazine "Die Bunte", may 2022 - through google translator)
We've finally made a breakthrough in Parkinson's

Q: How is the brain destroyed in Alzheimer's and Parkinson's?

A: All neurodegenerative diseases - whether Alzheimer's, Parkinson, ALS – have one thing in common: a different protein that previously has a normal function in the body,
begins for reasons we don't even know yet, to change its structure. It becomes pathological, forms clumps and kills the nerve cells in the brain.
We want to fight these proteins. But that is great for two reasons difficult: The therapies first have to go all the way to be brought to the brain. And then they are only allowed to attack the sick protein, not the healthy one.

Q: Where do you stand in Parkinson's research?

A: We've had a groundbreaking breakthrough this year.
We have developed an imaging method that early diagnosis of Parkinson's disease could. What has been known about Alzheimer's for 20 years was for Parkinson's not yet possible. We can now to the first take a look inside the brains of Parkinson's patients and make the pathological deposits visible. That is a incredibly important first step in diagnosis and treatment development of Parkinson's disease. It's a revolution from my point of view.

Q: Why?

A: This is the only way we can make early and precise diagnoses.
When the first symptoms of Alzheimer's appear, that's it destroys up to 70 percent of nerve cells. It already exists today a blood test with a probability of more than 90 percent ability to predict whether one will fall ill. I am convinced that at some point this will also be possible with Parkinson's will be. And I also firmly believe that against both Diseases it will eventually have vaccinations.