Local secretion should further enhance depth and durability. The first clinical data could come from China. I know two groups are running different trials testing either auto CAR-T or auto CAR-NK cell therapies. The former (just CD4+ T-cells) is designed to secret IL7/CCL19 and/or scFvs against PD-1/CTLA-4/TIGIT, while the latter IL7/CCL19 and/or scFvs against PD-1/CTLA-4/LAG-3.
* Moving AUTO6NG into the clinic soon
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