Innovation Pharmaceuticals Inc (IPIX)

[WhatchuTawlkinBoutWillis]

Recent Developments



As of the date of this filing, Brilacidin is being studied by independent researchers funded by US Government grants, as a potential broad-spectrum antiviral therapeutic for the treatment of viruses. Additionally, the antifungal properties of Brilacidin are being studied by several academic groups, including NIH/NIAID-affiliated researchers. We anticipate these studies to continue as long as researchers remain positive about the antiviral and antifungal properties and therapeutic potential of Brilacidin and government funding is available.



On November 15, 2022, the Company announced a scientific poster on the antiviral activity of Brilacidin was accepted for presentation at the 2022 Chemical and Biological Defense Science & Technology Conference. Data generated in alphaviruses and bunyaviruses showed that Brilacidin possesses both antiviral and anti-inflammatory properties, reinforcing its potential as a broad-spectrum antiviral.



On November 28, 2022, the Company announced BT BeaMedical Technologies (“BTL”), a company in which it maintains a minority stake, received FDA clearance for its surgical laser family. The BTL technology was cleared by the FDA in five different wavelengths and for soft tissue use in a number of clinical specialties.



On December 13, 2022, the Company reported new in vivo antifungal data showing Brilacidin’s potential for treating fungal keratitis. In an A. fumigatus mouse model, compared to control, Brilacidin reduced fungal burden and disease severity, while also improving corneal thickness.



On January 9, 2023, the Company announced BTL and Shina Systems Ltd., a company specializing in medical imaging software platforms, entered into a definitive strategic agreement. The agreement is intended to accelerate the development, regulatory clearance and commercial deployment of BTL laser technology for brain surgery.



In January 2023, the Company was notified by the United States Patent and Trademark Office (USPTO) that its US Patent Application 16/991812 – Host Defense Protein (HDP) Mimetics for Prophylaxis And/Or Treatment of Inflammatory Bowel Diseases of the Gastrointestinal Tract is allowed for issuance as a patent; Notice of Allowance was issued by USPTO on January 25, 2023.



In January 2023, the Company and University of São Paulo (USP), Brazil, entered into a collaborative research agreement related to investigating the broad-spectrum activity and treatment potential of Brilacidin in fungal diseases. Under terms of the agreement, USP researchers are to conduct pre-clinical efficacy, mechanism, resistance and immunological studies of Brilacidin against Aspergillosis, Cryptococcus and Candida, with USP eligible to receive future royalties should Brilacidin eventually be marketed as an antifungal.



https://www.otcmarkets.com/filing/html?id=16409574&guid=eY7-kFr_DsE_B3h