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Thursday, October 19, 2000 8:43:23 PM
High-throughput SNP profiling-To help us with our bottom line, we
provide contract SNP profiling services to the drug development
community. We call this service our SNiPdocTM service, and it is
targeted towards pharmaceutical companies. Many pharmaceutical
companies are seeking to enter into the field of Pharmacogenomics.
This new field of study could have a dramatic impact on overall
health care costs in the future. Furthermore, by having access to
pharmacogenomics data, pharmaceutical companies can focus their
clinical trials on segments of the population that are genetically
receptive to the treatment. Experimental drugs can be targeted to
individuals of a particular genotype, and genetic variations shown to
underlie a poor-response to a trial drug could be used as a basis for
eliminating the non-responding segment of the trial population from
the study. In this way, pharmaceutical companies can reduce drug
trial failures and the costs associated with them. Contracting this
work out to service providers is a viable option for many smaller
pharmaceutical companies who do not have the volume of work
necessary to justify the price of the equipment and expertise. At
DNAPrint Genomics, we offer multiple patient ? multiple SNP
sampling matricies designed on a custom, semi-custom or
predefined basis. We can use our proprietary PhenomixM databases
of medically relevant SNPs (numbering in the thousands of SNPs at
present), or design chips for your application de-novo. We will work
with your scientists to develop the experiments from beginning to
end, that suit your needs, and we can handle your project from
blood/tissue or DNA starting points. Data handling will be
customized for each client; data can be deposited in our secure SNP
relational databases system offering you the option of accessing
your data over the internet. Alternatively, we can burn and
hand-delivered CDs to you. As we develop our data mining
algorithms, you will have access to some of the most revolutionary
SNP pattern finding tools available anywhere. Using smart
PhenomixSM could help you identify overlapping sets of genotypes
associated with various phenotypes and/or phenotypic responses,
which you might otherwise miss if you conducted your studies on
your own or through another less-specialized facility.
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