Alzheimer’s: this could be an absolute breakthrough.
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PRX005, an investigational tri-epitopic antibody
If this is going after pathogens, especially viruses, we may finally be on the way to seeing a cure for Alzheimer’s.
… or at least I can hope
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Prothena Delivers 'Positive' Results From Phase 1 Study of Single-Dose Treatment for Alzheimer's Disease
2023-01-31 05:40:51 PM ET (MT Newswires)
05:40 PM EST, 01/31/2023 (MT Newswires) -- Prothena (PRTA) unveiled "positive" results from a topline Phase 1 single ascending dose study for the treatment of Alzheimer's disease.
Results from the study in healthy volunteers demonstrated dose-proportional PRX005 concentrations in plasma, with "robust" central nervous system penetration, the company said in a statement late Tuesday.
Single doses of PRX005 across three dose cohorts were "generally safe and well tolerated, meeting the primary objective of the study."
The company added the Phase 1 multiple ascending dose portion of the study is ongoing in healthy volunteers and patients with Alzheimer's disease. Topline results are expected by the end of 2023.
PRX005, an investigational tri-epitopic antibody, is one of three programs in the global neuroscience research and development collaboration between the company and Bristol Myers Squibb (BMY).
