Aptose Biosciences Inc (APTO): I'm well aware of Zilovertamab Vedot...

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Aptose Biosciences Inc (APTO)

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Re: dcaf7 post# 199

Friday, 01/27/2023 6:34:32 PM

Friday, January 27, 2023 6:34:32 PM

I'm well aware of Zilovertamab Vedotin. ONCT spun that out as the only product of Velos bio and then sold the company for $2.5B. They kept the ROR1-monoclonals and the ROR1-CAR-T program. They are just now initiating the CAR-T program in B-cell malignancies. I am very excited about that. Nemtabrutinib + Zilo(V) is worth watching. Need to also consider the side effects with ADCs. Is the Nem +Zilo(V) combination a pivotal for rrMCL?

We will see interim data from the r/rMCL registrational trial in about 2 years.

Back to Lux. Right now I am most interested in them getting G3 to RP2D and getting it into combinations in AML population. I don't see B-cell as the leading indications for early value creators. APTO is pretty focused on AML for the near future.

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Recent APTO News

Form 8-K - Current report • Edgar (US Regulatory) • 09/06/2024 08:15:12 PM
Form 8-K - Current report • Edgar (US Regulatory) • 09/05/2024 08:20:21 PM
Aptose Announces Results from Special Meeting of Shareholders • GlobeNewswire Inc. • 09/05/2024 08:15:00 PM
Form 8-K - Current report • Edgar (US Regulatory) • 08/30/2024 08:35:07 PM
Aptose Receives $10 Million Through a Facility Agreement with Hanmi; Negotiating Future Collaboration Agreement with Hanmi to Jointly Develop Tuspetinib • GlobeNewswire Inc. • 08/30/2024 08:30:02 PM
Form 8-K - Current report • Edgar (US Regulatory) • 08/15/2024 08:35:12 PM
Aptose Announces Adjournment of its Special Meeting of Shareholders • GlobeNewswire Inc. • 08/15/2024 08:30:00 PM
Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/08/2024 09:22:28 PM
Form 8-K - Current report • Edgar (US Regulatory) • 08/08/2024 09:15:13 PM
Aptose Reports Results for the Second Quarter 2024 • GlobeNewswire Inc. • 08/08/2024 09:06:51 PM
Form 8-K - Current report • Edgar (US Regulatory) • 07/26/2024 08:30:11 PM
Form 8-K - Current report • Edgar (US Regulatory) • 07/19/2024 09:00:14 PM
Aptose Announces Receipt of Deficiency Notice from Nasdaq • GlobeNewswire Inc. • 07/19/2024 09:00:00 PM
Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 07/17/2024 03:43:45 PM
Form 8-K - Current report • Edgar (US Regulatory) • 06/14/2024 11:40:15 AM
Form 8-K - Current report • Edgar (US Regulatory) • 06/03/2024 08:35:17 PM
Form 8-K - Current report • Edgar (US Regulatory) • 06/03/2024 02:32:05 PM
Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 06/03/2024 10:05:42 AM
Form 8-K - Current report • Edgar (US Regulatory) • 05/31/2024 12:05:15 PM
Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 05/15/2024 03:47:00 PM
Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 05/14/2024 09:06:23 PM
Form 8-K - Current report • Edgar (US Regulatory) • 05/14/2024 08:15:19 PM
Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 05/10/2024 03:35:32 PM
Form 8-K - Current report • Edgar (US Regulatory) • 05/06/2024 08:45:13 PM
Form 8-K - Current report • Edgar (US Regulatory) • 03/01/2024 10:00:16 PM

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